Nixon et al., Biological vulnerability to depression: linked structural and functional brain network findings. PMID: 24357570
A multimodal investigation of brain structure (cortical folding) structural and functional connectivity in 20 recovered-state patients with major depressive disorder with 20 healthy controls.
During task-performance, patients showed significant DMN hyperconnectivity; this was associated with hypogyrification of key default-mode network regions (bilateral precuneus).
A multimodal investigation of brain structure (cortical folding) structural and functional connectivity in 20 recovered-state patients with major depressive disorder with 20 healthy controls.
During task-performance, patients showed significant DMN hyperconnectivity; this was associated with hypogyrification of key default-mode network regions (bilateral precuneus).
- This is the first evidence of concomitant surface anatomical and functional network abnormalities in recovered-state depression
- Published in The British Journal of Psychiatry (IF: 6.6)